Learning-based Animal Models: Task-specific Focal Hand Dystonia

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Learning-based animal models: task-specific focal hand dystonia.

Dystonia is a disabling, involuntary disorder of movement that leads to writhing, twisting end-range movements or abnormal postures. Inadequate inhibition could account for excessive excitation and near synchronous co-contractions of agonists and antagonists. Dystonia may be generalized or specific, affecting only one part of the body or involving only a well-learned task (e.g., writing, keyboa...

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Abnormal Movement Preparation in Task-Specific Focal Hand Dystonia

Electrophysiological and behavioral studies in primary dystonia suggest abnormalities during movement preparation, but this crucial phase preceding movement onset has not yet been studied specifically with functional magnetic resonance imaging (fMRI). To identify abnormalities in brain activation during movement preparation, we used event-related fMRI to analyze behaviorally unimpaired sequenti...

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Velopharyngeal Dystonia: An Unusual Focal Task-specific Dystonia?

BACKGROUND Velopharyngeal dysfunction produces a nasal speech pattern because of the inability to close the nasal airway during speech, most often associated with anatomical abnormalities of the palate. CASE REPORT We describe two cases of possible velopharyngeal dystonia, a task-specific movement disorder causing a speech pattern similar to velopharyngeal dysfunction. Both patients experienc...

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Aberrant Oscillatory Activity during Simple Movement in Task-Specific Focal Hand Dystonia

In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the temporal and spatial characteristics of cortical activity during movement. A self-pa...

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ژورنال

عنوان ژورنال: ILAR Journal

سال: 2007

ISSN: 1084-2020

DOI: 10.1093/ilar.48.4.411